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Published in 1997: Antibody Therapeutics is a comprehensive evaluation of progress toward using humanized antibodies as a new generation of therapeutics. The humanized antibodies that have led the way in product approval are discussed as case studies, offering an insight into the preclinical and clinical data acquired during the regulatory approval process. Leading experts offer their findings as examples of what works and what does not, saving you time and making your research more cost effecti...

The focus of this book is on subjects related to drug delivery to the lung. The text spans topics from aerosol deposition through pharmaceutical chemistry and formulation to the final clinical evaluation of pharmaceutical products. Utilizing a multi-disciplinary approach, the chapters consider toxicology from the point of view of drugs and pharmaceutical excipients used in aerosols.

In this book, leading researchers in medicine and molecular pharmacology explain the cellular mechanisms that control airway smooth muscle. The means by which these are disrupted in disease, and the pharmacologic strategies by which they may be modified are discussed and future therapeutic interventions are identified. Aimed at specialists in pulmonology, this volume provides the clinician with the most up to date information on one of the core physiological processes in airway disease, and offe...

For introductory courses in phlebotomy. An easy-to-follow introduction to basic phlebotomy practice Phlebotomy Simplified is a step-by-step, practice-oriented approach to blood collection procedures for the beginning health care student. It can also serve as a practical reference guide for health care professionals responsible for blood and specimen collection in diverse settings, including hospitals, ambulatory clinics, home health care, and pediatric clinics. The 3rd edition has been reconfig...

Important scientific discoveries and ever-changing guidelines for how to identify and manage patients with hereditary cancer syndromes are constantly evolving. This Third Edition of Counseling About Cancer is completely updated and expanded to feature five entirely new chapters on breast cancer, colon cancer, other solid tumors, clients and families, and genetic test results and follow-up. This is the only reference and clinical book on the market for cancer genetics counselors and other hea...

An essential, up-to-date guide to the design of studies and selection of the correct QoL instruments for observational studies and clinical trials. Quality of Life (QoL) outcomes or Person/Patient Reported Outcome Measures (PROMs) are now frequently being used in randomised controlled trials (RCTs) and observational studies. This book provides a practical guide to the design, analysis and interpretation of studies that use such outcomes. QoL outcomes tend to generate data with discrete, bounded...

This large single volume dictionary defines and explains the great number of technical terms employed within those areas of neuropsychology and medicine that are strictly relevant to neuropsychology.

This book presents an up-to-date, accessible, and authoritative look into the rapidly emerging study of statistical adaptive design. Employing the R language throughout, it emphasizes the usefulness of adaptive design methods and technology in public health and research settings through practical examples and plentiful exercises. Special focus is on adaptive late-stage clinical trial designs as extensions of the highly successful group sequential methods that have been applied for more than two...

The National Service Framework for mental health aims to provide uniformly good systems so that mental health problems are detected and therefore treated early. This book sets out how learning more about mental health and reviewing current practice can be incorporated into a personal development plan or practice learning plan. It shows how to integrate quality improvements into everyday work and bridges the gap between theory and practice. Doctors nurses and practice managers can build up a per...

`New Trends and Advanced Techniques in Clinical Neurophysiology' is a compilation of expertly written articles by outstanding authors providing up-to-date reviews on the latest techniques in clinical neurophysiology and their diagnostic applications. The book contains much new and unpublished data, laid out in clearly defined chapters, covering exhaustively topics most actively debated during the past two years in the clinical neurophysiology literature. Topics include: new methods of signal pro...

Real-life cases for success on the neurology clerkship and shelf-exam Case Files (R): Neurology presents 50+ real-life cases that illustrate essential concepts in neurology. Each case includes a complete discussion, clinical pearls, references, high-yield presentation of key diagnostic and treatment information, USMLE-style review questions. With this system, students learn in the context of real patients, rather than merely memorize facts. This fourth edition has been thoroughly updated with t...

Applications of Microdialysis in Pharmaceutical Science focuses on the use of microdialysis in drug evaluation for different organs and tissues and pharmacokinetics. Introducing the basic principles of microdialysis, the book also covers quantification and validation, analytical considerations, pharmacodynamic studies, pharmacokinetics, clinical aspects, and other applications of microdialysis. Ideal for analytical chemists, pharmacists, and pharmacologists, this book uses easy-to-understand mo...

A FRESH EXAMINATION OF PRECISION MEDICINE'S INCREASINGLY PROMINENT ROLE IN THE FIELD OF ONCOLOGY Precision medicine takes into account each patient's specific characteristics and requirements to arrive at treatment plans that are optimized towards the best possible outcome. As the field of oncology continues to advance, this tailored approach is becoming more and more prevalent, channelling data on genomics, proteomics, metabolomics and other areas into new and innovative methods of practice....