Amphiphilic alpha-Helices in Protein-Membrane Interactions

by David A. Phoenix, Sarah R. Dennison, and Frederick Harris

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This first modern treatise on the subject collates knowledge from different fields and disciplines for a unified overview that was missing from the scientific literature until now.
Focusing on a small yet essential component of the cell's molecular machinery, this essential guide for structural biologists, bioengineers, and biotechnologists combines the latest findings on the structure, function, characterization and prediction of amphiphilic protein helices with illustrative examples of their biotechnological and biopharmaceutical applications. These include their use as molecular scaffolds for inhibitors of protein-protein interactions, building blocks for self-assembling nanostructures, drug carriers, antifreeze agents, and antimicrobials.
  • ISBN13 9783527803958
  • Publish Date 29 June 2022
  • Publish Status Active
  • Publish Country GB
  • Imprint Wiley-VCH Verlag GmbH