Homology Folding of Proteins: Application to Cytokine Engineering

by S. Srinivasan

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The homology modeling method is an important tool in protein engineering and drug design when an experimental 3D structure is not available. Development of distance geometry-based homology modeling offers a holistic approach to protein modeling thus expanding the scope of this method to protein threading and protein folding. This book is the first of its kind to give a complete account of the field including structural principles and sequence-to-structural relationships in the PDB. This book is intended for use by biologists and modelers who are new to homology modeling methods, and serves as a good starting point for further research.
  • ISBN10 3540636056
  • ISBN13 9783540636052
  • Publish Date 29 November 1997
  • Publish Status Active
  • Out of Print 12 November 2010
  • Publish Country DE
  • Publisher Springer-Verlag Berlin and Heidelberg GmbH & Co. KG
  • Imprint Springer-Verlag Berlin and Heidelberg GmbH & Co. K
  • Format Hardcover
  • Pages 143
  • Language English