This volume is an indispensable reference on the nature of immune defects in rodents and the special techniques necessary to maintain and breed them. The authors describe 64 inbred, hybrid, and mutant strains of rodents, each with some immune defect; explain mechanisms for ensuring genetic purity; and provide a standardized nomenclature for different varieties. Subsequent sections summarize and provide references on the genetics, pathophysiology, husbandry, and reproduction of each of the various strains as well as sound advice on planning for the selection, transportation, housing, and maintenance of these animals.
Table of Contents
- FRONT MATTER
- 1 INTRODUCTION
- 2 HEREDITARY IMMUNODEFICIENCIES
- 3 INDUCED IMMUNODEFICIENCIES
- 4 MAINTENANCE OF RODENTS REQUIRING ISOLATION
- 5 MATING SYSTEMS FOR MUTANTS
- 6 GENETIC MECHANISMS GOVERNING RESISTANCE OR SUSCEPTIBILITY . . .
- REFERENCES
- APPENDIX: HEMATOPOIETIC CELL-SURFACE ANTIGENS MENTIONED IN THE TEXT
- GLOSSARY
- INDEX
- ISBN10 0309092876
- ISBN13 9780309092876
- Publish Date 1 February 1989 (first published 1 January 1989)
- Publish Status Active
- Publish Country US
- Imprint National Academies Press
- Format Paperback
- Pages 260
- Language English