Developed as a one-stop reference source for drug safety and toxicology professionals, this book explains why mitochondrial failure is a crucial step in drug toxicity and how it can be avoided.
• Covers both basic science and applied technology / methods
• Allows readers to understand the basis of mitochondrial function, the preclinical assessments used, and what they reveal about drug effects
• Contains both in vitro and in vivo methods for analysis, including practical screening approaches for drug discovery and development
• Adds coverage about mitochondrial toxicity underlying organ injury, clinical reports on drug classes, and discussion of environmental toxicants affecting mitochondria
- ISBN13 9781119329732
- Publish Date 21 March 2018 (first published 23 February 2018)
- Publish Status Active
- Publish Country US
- Publisher John Wiley & Sons Inc
- Imprint Standards Information Network
- Format eBook
- Pages 816
- Language English
- URL http://wiley.com/remtitle.cgi?isbn=1119329736