The manufacture and applications of chiral compounds continue to develop. Building on the "case studies" format of the first volume, this text concentrates on different syntheses and the developments in the field. It presents a comprehensive picture of the technologies required for the production of optically active molecules on the multi-Kg to high tonnage scales, as well as illustrating the breadth of application of the products of these technologies. This volume is divided into sections on physical methods and classical resolutions, biological methods and the chiral pool, and asymmetric synthesis. These are preceded by a chapter dealing with regulatory issues for chiral drugs and two chapters on chiral drug development which illustrates how widely the industrial practitioner must cast the net in pursuit of practical production methods. The book should be of interest to applied chemists and organic synthetic chemists.
- ISBN10 0471966800
- ISBN13 9780471966807
- Publish Date 30 January 1997
- Publish Status Out of Print
- Out of Print 10 September 1998
- Publish Country GB
- Publisher John Wiley and Sons Ltd
- Imprint John Wiley & Sons Ltd
- Format Hardcover
- Pages 416
- Language English