Alexis Zegerman is a British actress and writer.

She won a British Independent Film Award for Best Supporting Actress for her role in Mike Leigh's 2008 film Happy-Go-Lucky. Other acting credits include: the original cast of Leigh's play Two Thousand Years (National Theatre, London, 2005); Caryl Churchill's play Seven Jewish Children (Royal Court Theatre, 2009); Arnold Wesker's play Chicken Soup with Barley (Royal Court Theatre, 2011); Nicholas Wright's play Travelling Light (National Theatre, 2012); and Tom Stoppard's play Leopoldstadt (West End, 2020).

As a writer her plays include: Shout (National Theatre Connections Festival, 2024); The Fever Syndrome (Hampstead Theatre, 2022); Holy Sh!t (Kiln Theatre, London, 2018); and Lucky Seven (Hampstead Theatre, 2008).