Mathukumalli Vidyasagar was born in Guntur, India in 1947. He received the B.S., M.S., and Ph.D. degrees in electrical engineering from the University of Wisconsin in Madison, in 1965, 1967, and 1969, respectively. From the next twenty years he taught mostly in Canada, before returning to his native India in 1989. Over the next twenty years, he built up two research organizations from scratch, first the Centre for Artificial Intelligence and Robotics under the Ministry of Defence, Government of India, and later the Advanced Technology Center in Tata Consultancy Services (TCS), India's largest software company. After retiring from TCS in 2009, he joined the University of Texas at Dallas as the Cecil & Ida Green Chair in Systems Biology Science, and he became the Founding Head of the Bioengineering Department. His current research interests are stochastic processes and stochastic modeling, and their application to problems in computational biology. He has received a number of awards in recognition of his research, including the 2008 IEEE Control Systems Award.