Born in Santiago, Chile, Gabriel Rodriguez began working as an illustrator in the late 90s and in 2002 started drawing books for IDW Publishing, including CSI, George Romero's Land of the Dead, Clive Barker's The Great and Secret Show, and Beowulf, amongst others.

In 2007, he co-created with Joe Hill the award-winning series Locke & Key. He continued developing other creator-owned projects: the Eisner-winning Little Nemo: Return to Slumberland, with Eric Shanower, and the gritty sci-fi adventure Onyx, with Chris Ryall. In 2016, he partnered with Hill once again for a comic adaptation of Hill's teleplays for a new version of Tales from the Darkside, as well as for a new Locke & Key story, "Small World."

His current project is Sword of Ages, a fantasy adventure series he is creating, writing and drawing.

He lives in Santiago with his wife, Catalina, and their kids, Jose Manuel, Matias, and Gabriel.