Henry Shykoff's family came to Canada from Poland when Henry was six years old. He grew up in Toronto and graduated from the University of Toronto medical school in 1949. He enjoyed 40 years of a distinguished medical career, which included teaching and research.

After retiring from the hospital, he pursued his love of storytelling and the study of paleoanthropology. His first book, Once Upon a Time Long, Long Ago, was a Silver Birch nominee.