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Theories and practices to assess critical information in a complex adaptive system Organized for readers to follow along easily, The Fitness of Information: Quantitative Assessments of Critical Evidence provides a structured outline of the key challenges in assessing crucial information in a complex adaptive system. Illustrating a variety of computational and explanatory challenges, the book demonstrates principles and practical implications of exploring and assessing the fitness of information...

This brief essay by the founder of scientific management has served for nearly a century as a primer for administrators and for students of managerial techniques. Although scientific management was developed primarily as a system for increasing productivity in industry, its principles have been applied to all kinds of large-scale enterprises, including operations with departments and agencies of the federal government. It is in this volume that Frederick Winslow Taylor gave the theory of scienti...

Demonstrates how nonresponse in sample surveys and censuses can be handled by replacing each missing value with two or more multiple imputations. Clearly illustrates the advantages of modern computing to such handle surveys, and demonstrates the benefit of this statistical technique for researchers who must analyze them. Also presents the background for Bayesian and frequentist theory. After establishing that only standard complete--data methods are needed to analyze a multiply--imputed set, the...

Learn the steps of the scientific method!

Thoroughly revised and expanded, the third edition of the Encyclopedia of Chromatography is an authoritative source of information for researchers in chemistry, biology, physics, engineering, and materials science. This quick reference and guide to specific chromatographic techniques and theory provides a basic introduction to the science and technology of the method, offering key references dealing with the methodology for analysis of specific chemicals and applications in industry. With a focu...

The education system in the United States is continually challenged to adapt and improve, in part because its mission has become far more ambitious than it once was. At the turn of the 20th century, less than one-tenth of students enrolled were expected to graduate from high school. Today, most people expect schools to prepare all students to succeed in postsecondary education and to prosper in a complex, fast-changing global economy. Goals have broadened to include not only rigorous benchmarks...

The enactment of the America COMPETES Act in 2006 (and its reauthorization in 2010), the increase in research expenditures under the 2009 American Recovery and Reinvestment Act (ARRA), and President Obama's general emphasis on the contribution of science and technology to economic growth have all heightened interest in the role of scientific and engineering research in creating jobs, generating innovative technologies, spawning new industries, improving health, and producing other economic and s...

In 2005, the National Research Council report Rising Above the Gathering Storm recommended a new way for the federal government to spur technological breakthroughs in the energy sector. It recommended the creation of a new agency, the Advanced Research Projects Agency-Energy, or ARPA-E, as an adaptation of the Defense Advanced Research Projects Agency (DARPA) model?widely considered a successful experiment that has funded out-of-the-box, transformative research and engineering that made possible...

Despite exciting advances in genome sequencing, isolating a protein from its expression system in its native form still presents a complex challenge. In High Throughput Protein Expression and Purification: Methods and Protocols, leading scientists detail the most successful protocols currently in use, including various high throughput cloning schemes, protein expression analysis, and production protocols. This volume describes the use of E. coli, insect, and mammalian cells, as well as cell-free...

Now in its fourth edition, this classic work clearly and concisely introduces the subject of logic and its applications. The first part of the book explains the basic concepts and principles which make up the elements of logic. The author demonstrates that these ideas are found in all branches of mathematics, and that logical laws are constantly applied in mathematical reasoning. The second part of the book shows the applications of logic in mathematical theory building with concrete examples th...

The isolation and structural characterization of substances present at very low concentrations, as is necessary to satisfy regulatory requirements for pharmaceutical drug degradants and impurities, can present scientific challenges. The coupling of HPLC with NMR spectroscopy has been at the forefront of cutting-edge technologies to address these issues. LC-NMR: Expanding the Limits of Structure Elucidation presents a comprehensive overview of key concepts in HPLC and NMR that are required to ach...